When we talk about running macro A/B tests, it's an example of a broader idea in growth: taking big swings.
When you make a landing page that's 80% shorter than your current landing page, that's a big swing.
Changing the color of your CTA button is NOT a big swing.
When you set up three Instagram ads — a screen recording video, an ad with only text in the image, and an image of someone tweeting about you — those are three big swings.
When you set up three Instagram ads — three screen recording videos with different body text — those are NOT big swings.
If you typically email users asking for a Yelp review, and then you A/B test texting them a meme like this asking for a review... that's a big swing.
(Maybe not one you should do. But a big swing nonetheless.)
In other words: "Big swings" means testing things that are wildly different from each other. Then doubling down on what works.
When you take big swings, you win big and you lose big; the results are very different between swings. But you get to cheat because you can only keep the ones that win - and prune away the losers. So you improve much faster over time.
Find big winners. Quickly get rid of losers. It's evolution at work.